The Relationship Between Quantitative C-Reactive Protein (CRP) Levels and Leukocyte Count in Patients with Pulmonary Tuberculosis Infection at Arifin Achmad Regional General Hospital
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Arniat Christiani Telambanua
Ressi Oktaviani
Background: Pulmonary tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis. C-Reactive Protein (CRP) and leukocyte count are indicators that can reflect the severity of infection in pulmonary TB patients. This study aims to analyze the correlation between quantitative CRP levels and leukocyte count in pulmonary tuberculosis patients. Methods: This was an observational analytic study with a cross-sectional approach conducted on 30 pulmonary TB patients at Arifin Achmad Hospital, Pekanbaru, who met the inclusion and exclusion criteria. CRP levels and leukocyte counts were obtained through laboratory tests, while demographic data were collected from patient medical records. Normality and linearity tests were conducted before the correlation analysis using linear regression tests. Results: The mean CRP level of patients was 84.14 ± 91.59 mg/L, with the lowest level being 0.71 mg/L and the highest being 316.7 mg/L. The mean leukocyte count was 10,481 ± 4,625.53 mm³, with the lowest count being 3,190 mm³ and the highest being 21,310 mm³. Bivariate analysis showed no significant correlation between CRP levels and leukocyte count in pulmonary TB patients (p = 0.378). Conclusion: There is no significant correlation between quantitative CRP levels and leukocyte count in pulmonary tuberculosis patients at Arifin Achmad Hospital, Pekanbaru. Further studies with larger sample sizes and longitudinal designs are needed to explore the relationship between these variables and their implications in pulmonary TB management.
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